The Warrens are best known for their involvement in the Amityville Horror case in which New York couple George and Kathy Lutz claimed that their house was haunted by a violent, demonic presence so intense that it eventually drove them out of their home. The Amityville Horror Conspiracy authors Stephen and Roxanne Kaplan characterized the case as a "hoax". Lorraine Warren told a reporter for The Express-Times newspaper that the Amityville Horror was not a hoax. The reported haunting was the basis for the 1977 book The Amityville Horror and 1979 and 2005 movies of the same name
In 1981, Arne Johnson was accused of killing his landlord, Alan Bono. Ed and Lorraine Warren had been called prior to the killing to deal with the alleged demonic possession of the younger brother of Mr. Johnson's fiancee. The Warrens subsequently claimed that Mr. Johnson was also possessed. At trial, Mr. Johnson attempted to plead Not Guilty by Reason of Demonic Possession, but was unsuccessful with his plea. The case was described in the 1983 book The Devil in Connecticut by Gerald Brittle.
1.3 Werewolf
The Warrens claim to have exorcised a "werewolf demon" in 1983. The subject of the case, Bill Ramsey, had bitten several people, believing himself to be a wolf. The events surrounding this case were later described in a 1991 book written by the Warrens, Werewolf: A True Story of Demonic Possession. No photos or video evidence was available to confirm the possibility and reasoning that Bill Ramsey was, indeed, possessed by a werewolf-type demon or evil spirit. The case remains filled with questions and skepticisms.
Pennsylvania residents Jack and Janet Smurl reported their home was disturbed by various supernatural phenomena, including sounds, smells and apparitions. The Warrens became involved and claimed that the Smurl home was occupied by three spirits and also a demon that allegedly sexually assaulted Jack and Janet Smurl.
In the 1970s, the Warrens claimed the Perron's Rhode Island home was haunted by demons because of a woman, presumed witch, who lived there in the early 19th century named Bathsheba Sherman, cursed the house. It is the subject of a 2013 film The Conjuring.
Other Notable Investigations Include:
1.6 Stepney Cemetery
Bishop Robert McKenna assisted the Warrens.
1.7 Borley Church
Ed and Lorraine Warren discuss the Borley Nun sightings
1.8 Union Cemetery (Easton, Connecticut)
Ed Warren saw a white lady dressed in white nightgown & bonnet
1.9 The Haunting in Connecticut
Ed and Lorraine Warren, who arrived and proclaimed the Snedeker house to be infested with demons.